Pesquisa | BVS IEC

1.

Rational attenuation of canine distemper virus (CDV) to develop a morbillivirus animal model that mimics measles in humans.

Schmitz, Katharina S; Rennick, Linda J; Tilston-Lunel, Natasha L; Comvalius, Anouskha D; Laksono, Brigitta M; Geers, Daryl; van Run, Peter; de Vries, Rory D; de Swart, Rik L; Duprex, W Paul.

J Virol ; 98(3): e0185023, 2024 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-38415596

2.

A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: protection of African green monkeys from COVID-19 disease.

Nambulli, Sham; Escriou, Nicolas; Rennick, Linda J; Demers, Matthew J; Tilston-Lunel, Natasha L; McElroy, Anita K; Barbeau, Dominique J; Crossland, Nicholas A; Hoehl, Ryan M; Schrauf, Sabrina; White, Alexander G; Borish, H Jacob; Tomko, Jaime A; Frye, Lonnie J; Scanga, Charles A; Flynn, JoAnne L; Martin, Annette; Gerke, Christiane; Hartman, Amy L; Duprex, W Paul.

J Virol ; 98(5): e0176223, 2024 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-38563762

3.

FeMV is a cathepsin-dependent unique morbillivirus infecting the kidneys of domestic cats.

Nambulli, Sham; Rennick, Linda J; Acciardo, Andrew S; Tilston-Lunel, Natasha L; Ho, Gregory; Crossland, Nicholas A; Hardcastle, Kathy; Nieto, Betsy; Bainbridge, Graeme; Williams, Tracey; Sharp, Claire R; Duprex, W Paul.

Proc Natl Acad Sci U S A ; 119(43): e2209405119, 2022 10 25.

Artigo em Inglês | MEDLINE | ID: mdl-36251995

4.

SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients.

Klimstra, William B; Tilston-Lunel, Natasha L; Nambulli, Sham; Boslett, James; McMillen, Cynthia M; Gilliland, Theron; Dunn, Matthew D; Sun, Chengun; Wheeler, Sarah E; Wells, Alan; Hartman, Amy L; McElroy, Anita K; Reed, Douglas S; Rennick, Linda J; Duprex, W Paul.

J Gen Virol ; 101(11): 1156-1169, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32821033

5.

Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20.

Feng, Junjie; Wickenhagen, Arthur; Turnbull, Matthew L; Rezelj, Veronica V; Kreher, Felix; Tilston-Lunel, Natasha L; Slack, Gillian S; Brennan, Benjamin; Koudriakova, Elina; Shaw, Andrew E; Rihn, Suzannah J; Rice, Charles M; Bieniasz, Paul D; Elliott, Richard M; Shi, Xiaohong; Wilson, Sam J.

J Virol ; 92(13)2018 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-29695422

6.

Generation of Recombinant Oropouche Viruses Lacking the Nonstructural Protein NSm or NSs.

Tilston-Lunel, Natasha L; Acrani, Gustavo Olszanski; Randall, Richard E; Elliott, Richard M.

J Virol ; 90(5): 2616-27, 2015 Dec 23.

Artigo em Inglês | MEDLINE | ID: mdl-26699638

7.

Establishment of a minigenome system for Oropouche virus reveals the S genome segment to be significantly longer than reported previously.

Acrani, Gustavo Olszanski; Tilston-Lunel, Natasha L; Spiegel, Martin; Weidmann, Manfred; Dilcher, Meik; Andrade da Silva, Daisy Elaine; Nunes, Marcio R T; Elliott, Richard M.

J Gen Virol ; 96(Pt 3): 513-523, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25491420

8.

Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence.

Tilston-Lunel, Natasha L; Hughes, Joseph; Acrani, Gustavo Olszanski; da Silva, Daisy E A; Azevedo, Raimunda S S; Rodrigues, Sueli G; Vasconcelos, Pedro F C; Nunes, Marcio R T; Elliott, Richard M.

J Gen Virol ; 96(Pt 7): 1636-50, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25735305

9.

Generation of Defective Interfering Particles of Morbilliviruses Using Reverse Genetics.

Rennick, Linda J; Duprex, W Paul; Tilston-Lunel, Natasha L.

Methods Mol Biol ; 2808: 57-70, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38743362

10.

Deletion of SenX3-RegX3, a key two-component regulatory system of Mycobacterium smegmatis, results in growth defects under phosphate-limiting conditions.

James, Jade N; Hasan, Zeeshaan-Ul; Ioerger, Thomas R; Brown, Amanda C; Personne, Yoann; Carroll, Paul; Ikeh, Melanie; Tilston-Lunel, Natasha L; Palavecino, Christian; Sacchettini, James C; Parish, Tanya.

Microbiology (Reading) ; 158(Pt 11): 2724-2731, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22956756

11.

Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses.

Nambulli, Sham; Xiang, Yufei; Tilston-Lunel, Natasha L; Rennick, Linda J; Sang, Zhe; Klimstra, William B; Reed, Douglas S; Crossland, Nicholas A; Shi, Yi; Duprex, W Paul.

Sci Adv ; 7(22)2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-34039613

12.

Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses.

Nambulli, Sham; Xiang, Yufei; Tilston-Lunel, Natasha L; Rennick, Linda J; Sang, Zhe; Klimstra, William B; Reed, Douglas S; Crossland, Nicholas A; Shi, Yi; Duprex, W Paul.

bioRxiv ; 2021 Feb 23.

Artigo em Inglês | MEDLINE | ID: mdl-33655253

13.

Sustained Replication of Synthetic Canine Distemper Virus Defective Genomes In Vitro and In Vivo.

Tilston-Lunel, Natasha L; Welch, Stephen R; Nambulli, Sham; de Vries, Rory D; Ho, Gregory W; Wentworth, David E; Shabman, Reed; Nichol, Stuart T; Spiropoulou, Christina F; de Swart, Rik L; Rennick, Linda J; Duprex, W Paul.

mSphere ; 6(5): e0053721, 2021 10 27.

Artigo em Inglês | MEDLINE | ID: mdl-34550005

14.

Rift Valley Fever Virus Infection Causes Acute Encephalitis in the Ferret.

Barbeau, Dominique J; Albe, Joseph R; Nambulli, Sham; Tilston-Lunel, Natasha L; Hartman, Amy L; Lakdawala, Seema S; Klein, Ed; Duprex, W Paul; McElroy, Anita K.

mSphere ; 5(5)2020 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-33115835

15.

SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected, hospitalized COVID-19 patients.

Klimstra, William B; Tilston-Lunel, Natasha L; Nambulli, Sham; Boslett, James; McMillen, Cynthia M; Gilliland, Theron; Dunn, Matthew D; Sun, Chengqun; Wheeler, Sarah E; Wells, Alan; Hartman, Amy L; McElroy, Anita K; Reed, Douglas S; Rennick, Linda J; Duprex, W Paul.

bioRxiv ; 2020 Jun 22.

Artigo em Inglês | MEDLINE | ID: mdl-32607507

16.

The Potential for Reassortment between Oropouche and Schmallenberg Orthobunyaviruses.

Tilston-Lunel, Natasha L; Shi, Xiaohong; Elliott, Richard M; Acrani, Gustavo Olszanski.

Viruses ; 9(8)2017 08 11.

Artigo em Inglês | MEDLINE | ID: mdl-28800086

17.

Sensitivity to BST-2 restriction correlates with Orthobunyavirus host range.

Varela, Mariana; Piras, Ilaria M; Mullan, Catrina; Shi, Xiaohong; Tilston-Lunel, Natasha L; Pinto, Rute Maria; Taggart, Aislynn; Welch, Stephen R; Neil, Stuart J D; Kreher, Felix; Elliott, Richard M; Palmarini, Massimo.

Virology ; 509: 121-130, 2017 09.

Artigo em Inglês | MEDLINE | ID: mdl-28628828

18.

Establishment of a minigenome system for Oropouche virus reveals the S genome segment to be significantly longer than reported previously

Acrani, Gustavo Olszanski; Tilston-Lunel, Natasha L; Spiegel, Martin; Weidmann, Manfred; Dilcher, Meik; Silva, Daisy Elaine Andrade da; Nunes, Márcio Roberto Teixeira; Elliott, Richard M.

ACRANI, Gustavo Olszanski et al. Establishment of a minigenome system for Oropouche virus reveals the S genome segment to be significantly longer than reported previously. Journal of General Virology, v. 96, pt. 3, p. 513-523, Mar. 2015. DOI: https://doi.org/10.1099/jgv.0.000005. Disponível em: https://www.microbiologyresearch.org/docserver/fulltext/jgv/96/3/513_vir000005.pdf?expires=1664300703&id=id&accname=guest&checksum=E5C3EE7327FDAFFA8B19B282ED25CD97.

Artigo em Inglês | Instituto Evandro Chagas (DSpace) | ID: ied-3858

19.

Establishment of a minigenome system for Oropouche virus reveals the S genome segment to be significantly longer than reported previously

Acrani, Gustavo Olszanski; Tilston-Lunel, Natasha L; Spiegel, Martin; Weidmann, Manfred; Dilcher, Meik; Silva, Daisy Elaine Andrade da; Nunes, Marcio R. T; Elliott, Richard M.

J. Gen. Virol ; 96(pt. 3): 513 - 523, mar. 2015.

Artigo em Inglês | Instituto Evandro Chagas (SOPHIA) | ID: iec-14819

20.

Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence

Tilston-Lunel, Natasha L; Hughes, Joseph; Acrani, Gustavo Olszanski; Silva, Daisy Elaine Andrade da; Azevedo, Raimunda S. S; Rodrigues, Sueli G; Vasconcelos, Pedro F. C; Nunes, Marcio R. T; Elliott, Richard M.

J. Gen. Virol ; 96(7): 1636 - 1650, Mar. 3, 2015. tab, ilus, mapas, graf

Artigo em Inglês | Instituto Evandro Chagas (SOPHIA) | ID: iec-14979

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Rational attenuation of canine distemper virus (CDV) to develop a morbillivirus animal model that mimics measles in humans.

A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: protection of African green monkeys from COVID-19 disease.

FeMV is a cathepsin-dependent unique morbillivirus infecting the kidneys of domestic cats.

SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected hospitalized COVID-19 patients.

Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20.

Generation of Recombinant Oropouche Viruses Lacking the Nonstructural Protein NSm or NSs.

Establishment of a minigenome system for Oropouche virus reveals the S genome segment to be significantly longer than reported previously.

Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence.

Generation of Defective Interfering Particles of Morbilliviruses Using Reverse Genetics.

Deletion of SenX3-RegX3, a key two-component regulatory system of Mycobacterium smegmatis, results in growth defects under phosphate-limiting conditions.

Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses.

Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses.

Sustained Replication of Synthetic Canine Distemper Virus Defective Genomes In Vitro and In Vivo.

Rift Valley Fever Virus Infection Causes Acute Encephalitis in the Ferret.

SARS-CoV-2 growth, furin-cleavage-site adaptation and neutralization using serum from acutely infected, hospitalized COVID-19 patients.

The Potential for Reassortment between Oropouche and Schmallenberg Orthobunyaviruses.

Sensitivity to BST-2 restriction correlates with Orthobunyavirus host range.

Establishment of a minigenome system for Oropouche virus reveals the S genome segment to be significantly longer than reported previously

Establishment of a minigenome system for Oropouche virus reveals the S genome segment to be significantly longer than reported previously

Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence